Antibody HAP1 Rabbit Polyclonal Antibody

HAP1 Rabbit Polyclonal Antibody

HAP1 Rabbit Polyclonal Antibody

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HAP1 Polyclonal Antibody
ABP58745-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of HAP1 from Human, Mouse, Rat. This HAP1 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human HAP1 protein

Polyclonal HAP1 Antibody
APR12325G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HAP1 . This antibody is tested and proven to work in the following applications:

HAP1 Polyclonal Antibody
ES9746-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against HAP1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

HAP1 Polyclonal Antibody
ES9746-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against HAP1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

HAP1 Rabbit pAb
A16333-100ul 100 ul
EUR 369.6

HAP1 Rabbit pAb
A16333-200ul 200 ul
EUR 550.8

HAP1 Rabbit pAb
A16333-20ul 20 ul
EUR 219.6

HAP1 Rabbit pAb
A16333-50ul 50 ul
EUR 267.6

Human Huntingtin Associated Protein 1 (HAP1) ELISA Kit
DLR-HAP1-Hu-48T 48T
EUR 620.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Huntingtin Associated Protein 1 (HAP1) in samples from tissue homogenates or other biological fluids.

Human Huntingtin Associated Protein 1 (HAP1) ELISA Kit
DLR-HAP1-Hu-96T 96T
EUR 807.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Huntingtin Associated Protein 1 (HAP1) in samples from tissue homogenates or other biological fluids.

Human Huntingtin Associated Protein 1 (HAP1) ELISA Kit
RDR-HAP1-Hu-48Tests 48 Tests
EUR 652.8

Human Huntingtin Associated Protein 1 (HAP1) ELISA Kit
RDR-HAP1-Hu-96Tests 96 Tests
EUR 907.2

Human Huntingtin Associated Protein 1 (HAP1) ELISA Kit
RD-HAP1-Hu-48Tests 48 Tests
EUR 625.2

Human Huntingtin Associated Protein 1 (HAP1) ELISA Kit
RD-HAP1-Hu-96Tests 96 Tests
EUR 867.6

Polyclonal HAP1 Antibody (Internal)
APR12326G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human HAP1 (Internal). This antibody is tested and proven to work in the following applications:

Polyclonal HAP1 Antibody (Internal)
APR12327G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HAP1 (Internal). This antibody is tested and proven to work in the following applications:

HAP1 Polyclonal Conjugated Antibody
C29811 100ul
EUR 476.4

HAP1 Antibody
4205-002mg 0.02 mg
EUR 206.18
Description: HAP1 Antibody: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. HAP1 was initially identified through a two-hybrid library screening; the binding of HAP1 to huntingtin correlated with the expansion of the polyglutamine tract. HAP1 also interacts with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), suggesting that HAP1 may play a role in vesicular trafficking or organelle transport. HAP1 is also involved with the huntingtin-enhanced BDNF transport along the cellular microtubles. Attenuation of this process led to the loss of neurotrophic support and neuronal toxicity, which suggests that loss of this function might contribute to pathogenesis. Several alternatively spliced isoforms have been described for HAP1.

HAP1 Antibody
4205-01mg 0.1 mg
EUR 523.7
Description: HAP1 Antibody: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. HAP1 was initially identified through a two-hybrid library screening; the binding of HAP1 to huntingtin correlated with the expansion of the polyglutamine tract. HAP1 also interacts with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), suggesting that HAP1 may play a role in vesicular trafficking or organelle transport. HAP1 is also involved with the huntingtin-enhanced BDNF transport along the cellular microtubles. Attenuation of this process led to the loss of neurotrophic support and neuronal toxicity, which suggests that loss of this function might contribute to pathogenesis. Several alternatively spliced isoforms have been described for HAP1.

HAP1 Antibody
24527-100ul 100ul
EUR 468

HAP1 Antibody
1-CSB-PA010129LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against HAP1. Recognizes HAP1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200

Hap1 Antibody
R35211-100UG 100 ug
EUR 399

HAP1 Antibody
R35816-100UG 100 ug
EUR 399

Polyclonal Goat Anti-HAP1 Antibody
AMM05941G 0.1 mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-HAP1 . This antibody is tested and proven to work in the following applications:

Polyclonal HAP1 Antibody (aa639-653)
AMRa00056G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HAP1 (aa639-653). This antibody is tested and proven to work in the following applications:

Anti-HAP1 antibody
PAab03753 100 ug
EUR 463.2

anti- HAP1 antibody
FNab03753 100µg
EUR 658.5
Description: Antibody raised against HAP1

Anti-HAP1 antibody
STJ118773 100 µl
EUR 332.4

Anti-HAP1 antibody
STJ190904 200 µl
EUR 236.4
Description: Unconjugated Rabbit polyclonal to HAP1

Anti-HAP1 antibody
STJ71050 100 µg
EUR 430.8

Hap1/ Rat Hap1 ELISA Kit
ELI-39039r 96 Tests
EUR 1063.2

HAP1 Peptide
4205P 0.05 mg
EUR 197.7
Description: (IN) HAP1 peptide

HAP1 Peptide
45-721P 0.1 mg
EUR 405.6
Description: (IN) HAP1 Peptide

HAP1 Peptide
45-722P 0.1 mg
EUR 405.6
Description: (CT) HAP1 (mouse) Peptide

HAP1 siRNA
20-abx902410
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

HAP1 siRNA
20-abx919071
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

HAP1 siRNA
20-abx919072
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

anti-HAP1
YF-PA27427 50 ug
EUR 435.6
Description: Mouse polyclonal to HAP1

Huntingtin-associated protein 1 (HAP1) polyclonal antibody
ABP-PAB-10627 100 ug Ask for price

HAP1 Antibody, HRP conjugated
1-CSB-PA010129LB01HU
  • EUR 380.40
  • EUR 402.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against HAP1. Recognizes HAP1 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

HAP1 Antibody, FITC conjugated
1-CSB-PA010129LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against HAP1. Recognizes HAP1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

HAP1 Antibody, Biotin conjugated
1-CSB-PA010129LD01HU
  • EUR 380.40
  • EUR 402.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against HAP1. Recognizes HAP1 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Anti-Hap1 (mouse) antibody
STJ71179 100 µg
EUR 430.8

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Human)
4-PAH923Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Associated Protein 1 (HAP1)

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Mouse)
4-PAH923Mu01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Huntingtin Associated Protein 1 (HAP1)

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Rat)
4-PAH923Ra01
  • EUR 310.80
  • EUR 3249.60
  • EUR 804.00
  • EUR 393.60
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Huntingtin Associated Protein 1 (HAP1)

Recombinant human HAP1
P1128 100ug Ask for price
Description: Recombinant protein for human HAP1

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Human), APC
4-PAH923Hu01-APC
  • EUR 414.00
  • EUR 3930.00
  • EUR 1094.40
  • EUR 528.00
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with APC.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Human), Biotinylated
4-PAH923Hu01-Biotin
  • EUR 373.20
  • EUR 2952.00
  • EUR 872.40
  • EUR 457.20
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with Biotin.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Human), Cy3
4-PAH923Hu01-Cy3
  • EUR 502.80
  • EUR 5190.00
  • EUR 1410.00
  • EUR 654.00
  • EUR 301.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with Cy3.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Human), FITC
4-PAH923Hu01-FITC
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with FITC.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Human), HRP
4-PAH923Hu01-HRP
  • EUR 379.20
  • EUR 3426.00
  • EUR 968.40
  • EUR 477.60
  • EUR 247.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with HRP.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Human), PE
4-PAH923Hu01-PE
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with PE.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Mouse), APC
4-PAH923Mu01-APC
  • EUR 421.20
  • EUR 4038.00
  • EUR 1122.00
  • EUR 538.80
  • EUR 266.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with APC.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Mouse), Biotinylated
4-PAH923Mu01-Biotin
  • EUR 379.20
  • EUR 3031.20
  • EUR 892.80
  • EUR 464.40
  • EUR 265.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with Biotin.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Mouse), Cy3
4-PAH923Mu01-Cy3
  • EUR 512.40
  • EUR 5334.00
  • EUR 1446.00
  • EUR 668.40
  • EUR 304.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with Cy3.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Mouse), FITC
4-PAH923Mu01-FITC
  • EUR 361.20
  • EUR 3254.40
  • EUR 921.60
  • EUR 454.80
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with FITC.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Mouse), HRP
4-PAH923Mu01-HRP
  • EUR 385.20
  • EUR 3519.60
  • EUR 992.40
  • EUR 486.00
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with HRP.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Mouse), PE
4-PAH923Mu01-PE
  • EUR 361.20
  • EUR 3254.40
  • EUR 921.60
  • EUR 454.80
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with PE.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Rat), APC
4-PAH923Ra01-APC
  • EUR 436.80
  • EUR 4254.00
  • EUR 1176.00
  • EUR 560.40
  • EUR 272.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with APC.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Rat), Biotinylated
4-PAH923Ra01-Biotin
  • EUR 390.00
  • EUR 3189.60
  • EUR 932.40
  • EUR 480.00
  • EUR 270.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with Biotin.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Rat), Cy3
4-PAH923Ra01-Cy3
  • EUR 532.80
  • EUR 5622.00
  • EUR 1518.00
  • EUR 697.20
  • EUR 313.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with Cy3.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Rat), FITC
4-PAH923Ra01-FITC
  • EUR 373.20
  • EUR 3427.20
  • EUR 964.80
  • EUR 471.60
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with FITC.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Rat), HRP
4-PAH923Ra01-HRP
  • EUR 398.40
  • EUR 3706.80
  • EUR 1039.20
  • EUR 505.20
  • EUR 255.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with HRP.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Rat), PE
4-PAH923Ra01-PE
  • EUR 373.20
  • EUR 3427.20
  • EUR 964.80
  • EUR 471.60
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with PE.

Huntingtin Associated Protein 1 (HAP1) Antibody
20-abx130407
  • EUR 543.60
  • EUR 159.60
  • EUR 1562.40
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Huntingtin Associated Protein 1 (HAP1) Antibody
20-abx128157
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Huntingtin Associated Protein 1 (HAP1) Antibody
20-abx129795
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Huntingtin Associated Protein 1 (Hap1) Antibody
abx431315-200ul 200 ul
EUR 460.8

Huntingtin Associated Protein 1 (HAP1) Antibody
abx432785-200ul 200 ul
EUR 460.8

Huntingtin Associated Protein 1 (HAP1) Antibody
abx233753-100ug 100 ug
EUR 610.8

Huntingtin Associated Protein 1 (HAP1) Antibody
20-abx172842
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

Huntingtin-associated protein 1 Antibody / HAP1
RQ6318 100 ug
EUR 419
Description: Huntingtin-associated protein 1 (HAP1) is a protein which in humans is encoded by the HAP1 gene. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Human HAP1 shRNA Plasmid
20-abx955940
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse HAP1 shRNA Plasmid
20-abx970748
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Rat HAP1 shRNA Plasmid
20-abx985492
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

HAP1 ELISA KIT|Human
EF010059 96 Tests
EUR 826.8

HAP1 Recombinant Protein (Rat)
RP204185 100 ug Ask for price

HAP1 Recombinant Protein (Rat)
RP204188 100 ug Ask for price

HAP1 Recombinant Protein (Human)
RP061680 100 ug Ask for price

HAP1 Recombinant Protein (Mouse)
RP140906 100 ug Ask for price

HAP1 Recombinant Protein (Mouse)
RP140909 100 ug Ask for price

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Human), APC-Cy7
4-PAH923Hu01-APC-Cy7
  • EUR 685.20
  • EUR 7716.00
  • EUR 2046.00
  • EUR 912.00
  • EUR 382.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with APC-Cy7.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Mouse), APC-Cy7
4-PAH923Mu01-APC-Cy7
  • EUR 699.60
  • EUR 7932.00
  • EUR 2100.00
  • EUR 933.60
  • EUR 388.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with APC-Cy7.

Huntingtin Associated Protein 1 (HAP1) Polyclonal Antibody (Rat), APC-Cy7
4-PAH923Ra01-APC-Cy7
  • EUR 729.60
  • EUR 8364.00
  • EUR 2208.00
  • EUR 976.80
  • EUR 402.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Huntingtin Associated Protein 1 (HAP1). This antibody is labeled with APC-Cy7.

Hap1 ORF Vector (Rat) (pORF)
ORF068063 1.0 ug DNA
EUR 607.2

Hap1 ORF Vector (Rat) (pORF)
ORF068064 1.0 ug DNA
EUR 607.2

HAP1 ORF Vector (Human) (pORF)
ORF020561 1.0 ug DNA Ask for price

Hap1 ORF Vector (Mouse) (pORF)
ORF046970 1.0 ug DNA
EUR 607.2

Hap1 ORF Vector (Mouse) (pORF)
ORF046971 1.0 ug DNA
EUR 607.2

HAP1 ELISA Kit (Human) (OKCD01042)
OKCD01042 96 Wells
EUR 997.2
Description: Description of target: Originally identified as neuronal protein that specifically associates with HTT/huntingtin and the binding is enhanced by an expanded polyglutamine repeat within HTT possibly affecting HAP1 interaction properties. Both HTT and HAP1 are involved in intracellular trafficking and HAP1 is proposed to link HTT to motor proteins and/or transport cargos. Seems to play a role in vesicular transport within neurons and axons such as from early endosomes to late endocytic compartments and to promote neurite outgrowth. The vesicular transport function via association with microtubule-dependent transporters can be attenuated by association with mutant HTT. Involved in the axonal transport of BDNF and its activity-dependent secretion; the function seems to involve HTT, DCTN1 and a complex with SORT1. Involved in APP trafficking and seems to faciltate APP anterograde transport and membrane insertion thereby possibly reducing processing into amyloid beta. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptors to synapses; the function is dependent on kinesin motor protein KIF5 and is disrupted by HTT with expanded polyglutamine repeat. Involved in regulation of autophagosome motility by promoting efficient retrograde axonal transport. Seems to be involved in regulation of membrane receptor recycling and degradation, and respective signal transduction, including GABA(A) receptors, tyrosine kinase receptors, EGFR, IP3 receptor and androgen receptor. Among others suggested to be involved in control of feeding behavior (involving hypothalamic GABA(A) receptors), cerebellar and brainstem development (involving AHI1 and NTRK1/TrkA), postnatal neurogenesis (involving hypothalamic NTRK2/TrkB), and ITPR1/InsP3R1-mediated Ca2+ release (involving HTT and possibly the effect of mutant HTT). Via association with DCTN1/dynactin p150-glued and HTT/huntingtin involved in cytoplasmic retention of REST in neurons. May be involved in ciliogenesis. Involved in regulation of exocytosis. Seems to be involved in formation of cytoplasmic inclusion bodies (STBs). In case of anomalous expression of TBP, can sequester a subset of TBP into STBs; sequestration is enhanced by an expanded polyglutamine repeat within TBP. HAP1-containing STBs have been proposed to play a protective role against neurodegeneration in Huntigton disease (HD) and spinocerebellar ataxia 17 (SCA17).1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.9"Huntingtin regulates RE1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain protein (RILP) and dynactin p150 Glued."_x005F_x005F_x000D_Shimojo M._x005F_x005F_x000D_J. Biol. Chem. 283:34880-34886(2008) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.113 ng/mL

Hap1 sgRNA CRISPR Lentivector set (Rat)
K6830601 3 x 1.0 ug
EUR 406.8

HAP1 sgRNA CRISPR Lentivector set (Human)
K0928701 3 x 1.0 ug
EUR 406.8

Hap1 sgRNA CRISPR Lentivector set (Mouse)
K3962801 3 x 1.0 ug
EUR 406.8

Recombinant Huntingtin Associated Protein 1 (HAP1)
4-RPH923Hu01
  • EUR 588.79
  • EUR 280.80
  • EUR 1877.95
  • EUR 705.98
  • EUR 1291.97
  • EUR 469.20
  • EUR 4514.88
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Huntingtin Associated Protein 1 expressed in: E.coli

HAP1 Rabbit Polyclonal Antibody